Major Depressive Disorder

A) EPIDEMIOLOGY

Global Impact

Prevalence

B) PROGNOSIS

Recovery

Residual symptoms

Relapse / Recurrence

Morbidity / Mortality

Suicide

Comorbidity

Bipolar Depression

Sub-Types

Special Populations

Differences with age

C) ETIOLOGY / PATHOPHYSIOLOGY

Hypothalamic Pituitary Adrenal (HPA) axis

Neuroanatomy

Genetics

Sleep